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1、Nomenclature     
English name:Bacitracin

2、Structural formula

Molecular formula of Bacitracin A：C₆₆H₁₀₃N₁₇O₁₆S   
Molecular mass of Bacitracin A：1422.69   
CAS No.：1405-87-4

3、Mechanism and clinical use:

Bacitracin is used as a polypeptide antibiotic. Bacitracin has bactericidal action for Gram-positive bacteria & Gram-negative coccobacteria, diplococcus lanceolatus, staphylococcus, gonococcus, diplococcus intracellularis, leptospiral, etc. The mechanism of action: act on cell wall and affect protoplast, damage cellular plasma membrane and affect permeability.

It is mainly used for infection of penicillin-resistant staphylococcus, also used for skin infection, etc. At a certain concentration, it has a strong antibacterial effect on systemic and local infections caused by Gram-positive bacteria. Its antibacterial spectrum is similar to that of penicillin G. It is often used in combination with polymyxin and neomycin to obtain the antibacterial spectrum.

4、Executive standard

5、Qualification certificate

6、Packaging size specification

Inner package: single-layer polyethylene bag and aluminum foil bag.

Outer package: fiber drum.

Packaging size: 10 kg/drum 

1、Nomenclature
English name： Bacitracin Zinc

2、Stuctural formula

Molecular formula：C₆₆H₁₀₃N₁₇O₁₆SZn    
Molecular mass：1486.07   
CAS No.：1405-89-6

3、Mechanism and clinical use:

Bacitracin Zinc is used as a polypeptide antibiotic. Bacitracin Zinc has bactericidal action for Gram-positive bacteria. The mechanism of action: act on cell wall, bind with cell wall of sensitive bacteria, damage cell wall integrity, and give rise to outflow of important materials in cell.

It effectively inhibits gram positive bacteria and some gram negative bacteria. Bacitracin resistance was slow, and there was no cross-resistance with other antibiotics. Promote the growth of livestock and poultry, improve feed conversion rate.

On June 2019, API Bacitracin Zinc was granted “written confirmation for active substance exported to EU”.

4、Executive standards
USP

5、Qualification certificate
WC license, US DMF registration number

6、Packaging size specification

Inner package: single-layer polyethylene bag and aluminum foil bag.

Outer package: fiber drum.

Packaging size: 10 kg/drum

1、Nomenclature

English name：Fusidic Acid

2、Structural formula

Molecular formula：C₃₁H₄₈O₆·1/2 H₂O    
Molecular mass：525.7          
CAS No.：6990-06-3

3、Mechanism and clinical use:

Fusidic Acid was extracted in 1962 for the first time by the Danish LEO Pharma from the fermentation broth of Fusidium coccineum. It is a narrow-spectrum, high-efficiency and anti gram-positive bacteria antibiotic widely used in foreign countries. Fusidic Acid, as a typical high efficiency antibiotic, although has been widely used in foreign countries for more than 30 years (few used in domestic clinical), still keeps relatively strong antibacterial activity and very low resistance to most staphylococcus strain, more and more receives people’s attention, and becomes new selection of anti resistant staphylococcus aureus (MRSA).

Fusidic Acid is a kind of antibiotic product for curing infections caused by sensitive bacteria especially staphylococci, such as carious osteitis, blood poisoning, encarditis, repeated infected cystic fibrosis, pneumonia, cutaneo-infection & soft tissue infection, surgery infection & wound infection.

On Feb 2020, API Fusidic Acid was granted “written confirmation for active substance exported to EU”.

On June 2020, API Fusidic Acid was granted CEP certificate.

On Feb 2020，Obtain the EU GMP certificate.

4、Executive standards
CP、EP、IP

5、Qualification certificate
Registration "A" status of raw material packaging, Notification of Approval of marketing application for chemical API, WC, COPP, CEP, EUGMP, US DMF registration number, India Registration certificate, Brazil registration, Malaysia registration, etc.

6、Packaging size specification

Inner package: single-layer polyethylene bag and aluminum foil bag.

Outer package: fiber drum.

Packaging size: 20 kg/drum

Sodium Fusidate

1、Nomenclature
English name：Sodium Fusidate

2、Structural formula

Molecular formula：C₃₁H₄₇NaO₆            
Molecular mass：538.70              
CAS No.：751-94-0

3、Mechanism and clinical use:

Sodium fusidate is obtained by extracting fusidic acid from the fermentation broth of fusidium coccineum, and then salting it with sodium hydroxide. It is a narrow-spectrum and highly effective antibiotic against Gram-positive bacteria widely used abroad. Sodium fusidate has a bactericidal effect by inhibiting bacterial protein synthesis and has a potent antibacterial effect against a range of Gram-positive bacteria. It has been paid more and more attention to maintain strong antibacterial activity and low resistance rate against the vast majority of staphylococcal strains, and has become a new choice for resistant staphylococcus aureus.

Sodium Fusidate is a kind of antibiotic product for curing infections caused by sensitive bacteria especially staphylococci, such as carious osteitis, blood poisoning, encarditis, repeated infected cystic fibrosis, pneumonia, cutaneo-infection & soft tissue infection, surgery infection & wound infection.

4、Executive standards
CP、EP、IP

5、Qualification certificate
WC license, COPP certificate, CEP certificate, US DMF registration number, Indian registration certificate.

6、Packaging size specification

Inner package: single-layer polyethylene bag and aluminum foil bag.

Outer package: fiber drum.

Packaging size: 15 kg/drum